Clinical Trials

There is a clinical trial combining a BET inhibitor, ZEN003694, with chemotherapy treatment (etoposide and cisplatin) for adult and pediatric patients (12-17 Years) with NUT Carcinoma. Additional information about this trial can be found at the following link: https://clinicaltrials.gov/ct2/show/NCT05019716

There is a clinical trial studying an investigational drug called BMS-986158 as a possible treatment for NUT carcinoma in young adults and children (Age ≤21 years). Additional information about this trial can be found at the following link:
https://clinicaltrials.gov/ct2/show/NCT03936465

There is a clinical trial utilizing a dual BET and CBP/p300 inhibitor in adult patients with targeted advanced solid tumors (including NUT Carcinoma). Additional information about this trial can be found at the following link: https://clinicaltrials.gov/study/NCT05488548?term=NCT05488548&rank=1

There is a clinical trial combining a BET inhibitor, ZEN003694, with CDK inhibitor, abemaciclib, for adult and pediatric patients (12-17 Years) with NUT Carcinoma. Additional information about this trial can be found at the following link: https://clinicaltrials.gov/study/NCT05372640

For inquiries regarding entry into these trials, please contact Dr. Chris French at cfrench@bwh.harvard.edu , tel 617 525-4415.